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Effect of the CYP2C9*3 allele on lornoxicam metabolism

✍ Scribed by Ya-Li Liu; Wei Zhang; Zhi-Rong Tan; Dong-Sheng Ouyang; Chen-hui Luo; Zhao-Qian Liu; Yu Qiu; Yao Chen; Yi-Jing He; Gan Zhou; Hong-Hao Zhou

Book ID
116346937
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
110 KB
Volume
364
Category
Article
ISSN
0009-8981

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πŸ“œ SIMILAR VOLUMES

Role of human liver microsomal CYP2C9 in
Role of human liver microsomal CYP2C9 in the biotransformation of lornoxicam
✍ P. Bonnabry; T. Leemann; P. Dayer πŸ“‚ Article πŸ“… 1996 πŸ› Springer 🌐 English βš– 447 KB

## Objective: The nature of the enzyme(s) catalysing the biotransformation of lornoxicam to one of its major metabolites, 5'-hydroxy-lornoxicam, has been investigated in human liver microsomes. the reaction kinetics were characterised, the affinity of lornoxicam for three major human drug metabolis