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EFFECT OF THE ANTIDEPRESSANT MAPROTILINE ON CA2+ MOVEMENT AND PROLIFERATION IN HUMAN PROSTATE CANCER CELLS

✍ Scribed by Shu-Shong Hsu; Wei-Chuan Chen; Yuk-Keung Lo; Jin-Shiung Cheng; Jeng-Hsien Yeh; He-Hsing Cheng; Jin-Shyr Chen; Hong-Tai Chang; Bang-Ping Jiann; Jong-Khing Huang; Chung-Ren Jan


Book ID
108937500
Publisher
John Wiley and Sons
Year
2004
Tongue
English
Weight
340 KB
Volume
31
Category
Article
ISSN
0305-1870

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## Abstract The present study evaluated the effects of thimerosal, a vaccine preservative, on cytosolic free Ca^2+^ concentrations ([Ca^2+^]~i~) in human prostate cancer cells (PC3). Thimerosal (10–200 ¡M) increased [Ca^2+^]~i~ in a concentration‐dependent manner. The Ca^2+^ signal was reduced part