Effect of thymidine on the toxicity and
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V. Bruce Grossie; Manuel Valdivieso; Benjamin Drewinko; Ti Li Loo
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Article
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1984
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Springer
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English
β 340 KB
The effect of thymidine (TdR) on the preclinical toxicity of cis-diamminedichloroplatinum (II) (DDP) was investigated in the BDF 1 mouse and the Sprague-Dawley rat. The effect of TdR on the antitumor activity of DDP was investigated using the ascites P388 murine leukemia model. TdR at 500 mg/kg cons