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Effect of the Antiarrhythmic Drug Procainamide on the Toxicity and Antitumor Activity ofcis-Diamminedichloroplatinum(II)

✍ Scribed by Mauro Esposito; Maurizio Viale; Maria Ornella Vannozzi; Antonio Zicca; Angela Cadoni; Franco Merlo; Luca Gogioso


Book ID
112266209
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
602 KB
Volume
140
Category
Article
ISSN
0041-008X

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✍ V. Bruce Grossie; Manuel Valdivieso; Benjamin Drewinko; Ti Li Loo πŸ“‚ Article πŸ“… 1984 πŸ› Springer 🌐 English βš– 340 KB

The effect of thymidine (TdR) on the preclinical toxicity of cis-diamminedichloroplatinum (II) (DDP) was investigated in the BDF 1 mouse and the Sprague-Dawley rat. The effect of TdR on the antitumor activity of DDP was investigated using the ascites P388 murine leukemia model. TdR at 500 mg/kg cons