## Abstract Male F344 rats were fed __N__‐[4‐(5‐nitro‐2‐furyl)‐2‐thiazolyl]formamide (FANFT) for up to 4 wk, then were given the basal diets (Prolab 3200 or AIN‐76A) with or without 5% sodium saccharin for up to 100 wk. Eleven transitional cell carcinomas (TCCs), one undifferentiated carcinoma, and
✦ LIBER ✦
Effect of the altered codon position and encoded amino acid on transformation by point mutation in ras genes
✍ Scribed by Silvia Guerrero Caballero; Ramón Mangues Bafalluy
- Book ID
- 110647523
- Publisher
- Springer Milan
- Year
- 2002
- Tongue
- Spanish
- Weight
- 124 KB
- Volume
- 4
- Category
- Article
- ISSN
- 1699-048X
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Activating mutations in and expression of the Ha-ras gene were examined in benign and malignant female Sprague-Dawley rat mammary gland tumors induced by the heterocyclic amine 2-amino-1-methyl-6phenylimidazo[4,5-b]pyridine (PhIP) and promoted by a diet high in polyunsaturated fat. Ha-ras mutations