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Effect of the Aldose Reductase Inhibitor Tolrestat on Nerve Conduction Velocity, NA/K ATPase Activity, and Polyols in Red Blood Cells, Sciatic Nerve, Kidney Cortex, and Kidney Medulla of Diabetic Rats

โœ Scribed by Denis Raccah; Thierry Coste; Norman E. Cameron; Dominique Dufayet; Philippe Vague; Thomas C. Hohman


Book ID
114343799
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
140 KB
Volume
12
Category
Article
ISSN
1056-8727

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๐Ÿ“œ SIMILAR VOLUMES


Aldose reductase inhibition with imirest
โœ A. L. Carrington; C. B. Ettlinger; N. A. Calcutt; D. R. Tomlinson ๐Ÿ“‚ Article ๐Ÿ“… 1991 ๐Ÿ› Springer ๐ŸŒ English โš– 633 KB

This study describes reduced motor nerve conduction velocity and increased resistance to hypoxia-induced conduction failure in sciatic nerves of rats after four weeks of streptozotocin-induced diabetes (both effects were significant at p < 0.05). These changes occurred in the absence of any deficit