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Effect of the 5-lipoxygenase inhibitor piriprost on superoxide production by human neutrophils

โœ Scribed by Flament, J; Schandene, L; Boeynaems, J.-M

Book ID
122788248
Publisher
Elsevier Science
Year
1988
Tongue
English
Weight
591 KB
Volume
34
Category
Article
ISSN
0952-3278

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A reverse-phase-HPLC/tandem mass spectrometric method (LC/MS/MS) was developed for the quantitation of leukotriene B4 (LTB4), the 5-lipoxygenase product, 5-hydroxyeicosatetraenoic acid (5-HETE), as well as the omega-oxidation metabolites of LTB4, 20-hydroxy-LTB4, and 20-carboxy-LTB4. Electrospray-ge