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Effect of the 21-aminosteroid on nuclear factor-κB activation of Kupffer cells in endotoxin shock

✍ Scribed by Kazuro Okada; Seiji Marubayashi; Kazuyuki Fukuma; Kazuo Yamada; Kiyohiko Dohi


Book ID
117849104
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
121 KB
Volume
127
Category
Article
ISSN
0039-6060

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Reperfusion after liver transplantation results in the induction of tumor necrosis factor-␣ (TNF␣) as well as activation of the stress-associated signaling proteins, c-Jun N-terminal kinase (JNK), activating protein-1 (AP-1), and nuclear factor-B (NF-B). To test the hypothesis that Kupffer cells are