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Effect of Tetrodotoxin on Membrane Currents in Mammalian Cardiac Fibres

✍ Scribed by DUDEL, J.; PEPER, K.; RÜDEL, R.; TRAUTWEIN, W.

Book ID
109655178
Publisher
Nature Publishing Group
Year
1967
Tongue
English
Weight
226 KB
Volume
213
Category
Article
ISSN
0028-0836

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We examined the effects of calcitonin gene-related peptide (CGRP) on the membrane currents of single atrial and ventricular cells of guinea pig heart. The tightseal whole-cell voltage-clamp technique was used. In atrial cells, like isoproterenol, CGRP increased the L-type Ca channel current (ICa.L)