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Effect of temperature on proximal tubular acidification

✍ Scribed by C. R. Rubio; O. C. Mangili; G. B. Mello; G. Malnic

Publisher
Springer
Year
1982
Tongue
English
Weight
642 KB
Volume
393
Category
Article
ISSN
0031-6768

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## Abstract Cyclosporine A (CsA) is known to have direct toxicity to renal tubular cells. Its toxicity may be mediated by intracellular calcium because CsA increases intracellular calcium concentration and enhances the activities of calcium‐dependent calpains and caspases. Calbindin‐D~28k~, a cytos