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Effect of t-PA on the generation of PAI-1, fibrin deposits and mortality in endotoxin-induced intravascular coagulation (DIC) in rabbits

✍ Scribed by Páramo, J.A.; Paloma, M.J.; Rifón, J.; Fernández, M.J.; Sarrá, J.; Rocha, E.


Book ID
122053503
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
142 KB
Volume
4
Category
Article
ISSN
0268-9499

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The effect of low molecular weight heparin (LMWH) with or without antithrombin III (AT III) has been studied in a rabbit model of disseminated intravascular coagulation (DIC) induced by continuous infusion of 100 µg/kg/hr of Escherichia coli endotoxin for 6 hr. LMWH (5 and 10 IU/kg/hr/6 hr), alone o