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Effect of surgical menopause and Paget's disease of bone on the isomerization of type I collagen carboxyterminal telopeptide: evolution after antiresorptive therapy

✍ Scribed by Pilar Peris; Luisa Alvarez; Ana Monegal; Núria Guañabens; Magdalena Durán; Mónica Echevarría; Inmaculada Ros; Antonio M. Ballesta; José Muñoz-Gómez

Publisher: Springer
Year: 2002
Tongue: English
Weight: 76 KB
Volume: 20
Category: Article
ISSN: 0914-8779
DOI: 10.1007/s007740200016

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## Objective: We have previously shown that the woven pagetic bone in patients with paget's disease is characterized by an impaired degree of beta-isomerization of c-telopeptides of type i collagen molecules, which results in a preferential urinary excretion of nonisomerized type i collagen c-telop