Effect of surgery on monocyte function
โ Scribed by M. Oladimeji; A. D. Grimshaw; M. Baum; K. G. Patterson; A. H. Goldstone
- Publisher
- John Wiley and Sons
- Year
- 1982
- Tongue
- English
- Weight
- 282 KB
- Volume
- 69
- Category
- Article
- ISSN
- 0007-1323
No coin nor oath required. For personal study only.
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Cytokines produced by macrophages in the periprosthetic membranes surrounding joint replacements have been implicated as causal agents in osteolysis and prosthetic loosening. The present study characterizes the response of human peripheral blood monocytes to titanium particles. Monocytes were obtain
## Abstract ## Objective RANKL, a member of the tumor necrosis factor superfamily, is a central regulator of osteoclast recruitment and activation. Whether RANKL affects monocyte locomotion in vitro via RANK and a possible signaling pathway were investigated. ## Methods Monocytes were obtained f