Key word\ cirrhow. liver, c h o n tetr,~hloride. pharmdcokinetics This study inbestigated the conditions necessary to produce a predictable yield of cirrhosis in rats. A previously published method, using carbon tetrachloride, was used as a basis for the study. Histopathology was used in a semi-quan
Effect of stimulation of hepatic macrophages on the development of cirrhosis of the liver in rats
β Scribed by S. N. Kutina; D. N. Mayanskii
- Publisher
- Springer US
- Year
- 1981
- Tongue
- English
- Weight
- 805 KB
- Volume
- 92
- Category
- Article
- ISSN
- 0007-4888
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We studied the effects of a series of vasodilators on intrahepatic vascular resistance of isolated perfused cirrhotic rat livers in basal conditions and during norepinephrine-induced vasoconstriction. Cirrhosis was induced by repeated intraperitoneal injections of carbon tetrachloride. The vasodilat
Tumour cells from a squamous carcinoma (approximately 2.5 X 10(5)) were injected intraportally into a syngeneic strain of rats to produce liver metastases 14 days later. Kupffer cells were stimulated by Corynebacterium parvum (7 mg or 1 mg i.v.) and zymosan (10 mg intraportally). Kupffer cell activi