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Effect of Staurosporine on Suppression of Heat Shock Gene Expression and Thermotolerance Development in HT-29 Cells

✍ Scribed by S.H. Kim; J.H. Kim; G. Erdos; Y.J. Lee

Book ID
115573075
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
279 KB
Volume
193
Category
Article
ISSN
0006-291X

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## Abstract Summary: We examined the effect of histone deacetylase inhibitors (HDIs), trichostatin A (TSA), valproic acid (VPA), and sodium butyrate (NaB) on heat shock protein (hsp) gene expression during early __Xenopus laevis__ development. HDIs enhance histone acetylation and result in the reli