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Effect of somatostatin on adenylate cyclase activity in normal and neoplastic thyroid tissue

✍ Scribed by Allan E. Siperstein; Kenneth E. Levin; Elizabeth T. Gum; Orlo H. Clark

Publisher
Springer
Year
1992
Tongue
English
Weight
692 KB
Volume
16
Category
Article
ISSN
0364-2313

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## Abstract Although alterations in adenylate cyclase (AC) activity and somatostatin (SRIF) receptor density have been reported in Alzheimer's disease, the effects of amyloid β‐peptide (AΞ²) on these parameters in the hippocampus are unknown. Our aim was to investigate whether the peptide fragment A