Effect of solvent on the separation of oligomer polyethers on sephadex LH-20

✍ Scribed by D Berek; D. Bakoš

• Publisher: Elsevier Science
• Year: 1974
• Tongue: English
• Weight: 584 KB
• Volume: 91
• Category: Article
• ISSN: 1873-3778
• DOI: 10.1016/s0021-9673(01)97903-8

✦ Synopsis

The selectivity of gel chromatographic separation of oligomers and low-molecular-weight compounds can be remarkably increased by the appropriate application of sorption effects. Effective fractionation of oligomers is achieved in systems where only the end groups of molecules are sorbed strongly on the gel. The extent of sorption can be influenced by the choice of a suitable separation system. The method is demonstrated by the fractionation of polyether oligomers on Sephadex LH-20 in various solvents.