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Effect of SKF-525A on liver metabolism and hepatotoxicity of tri- and dibutyltin compounds in mice

โœ Scribed by Shunji Ueno; Takashi Suzuki; Nobuyuki Susa; Yoshinori Furukawa; Masayasu Sugiyama

Publisher
Springer-Verlag
Year
1997
Tongue
English
Weight
182 KB
Volume
71
Category
Article
ISSN
0340-5761

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Mice pretreated with the monoamine oxidase inhibitor pargyline showed a dose-dependent increase in hyperactivity for up to 2 h following injections of N,Ndimethyltryptamine (DMT: 0.5-8.0 mg/kg). Hyperactivity was related to a linear increase in whole brain concentrations of DMT as measured by a new