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Effect of size on other physical properties of granules and their corresponding tablets

โœ Scribed by Alan M. Marks; John J. Sciarra

Book ID
102914585
Publisher
John Wiley and Sons
Year
1968
Tongue
English
Weight
822 KB
Volume
57
Category
Article
ISSN
0022-3549

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Understanding size enlargement and harde
Understanding size enlargement and hardening of granules on tabletability of unlubricated granules prepared by dry granulation
โœ Sarsvatkumar Patel; Sandeepkumar Dahiya; Changquan Calvin Sun; Arvind Kumar Bans ๐Ÿ“‚ Article ๐Ÿ“… 2011 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 379 KB ๐Ÿ‘ 1 views

The mechanism of loss of "reworkability" or tabletability of dry granulated microcrystalline cellulose (MCC) was investigated in relation to both granule size enlargement and granule hardness. Slugs of MCC were prepared under three pressures (12.5, 37.5, and 93.8 MPa) and tabletability (tensile stre