Effect of siRNA targeted against MKK4 on myostatin-induced downregulation of differentiation marker gene expression

Effects of physiological mechanical stra

Effects of physiological mechanical strains on the release of growth factors and the expression of differentiation marker genes in human osteoblasts growing on Ti-6Al-4V

✍ Petros A. Kokkinos; Ioannis K. Zarkadis; Dimitris Kletsas; Despina D. Deligianni 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 366 KB 👁 2 views

## Abstract Mechanical loading factors at the bone‐implant interface are critical for the osseointegration and clinical success of the implant. The aim of the present investigation was to study the effects of mechanical strain on the orthopedic biomaterial Ti‐6Al‐4V/osteoblast interface, using an _