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Effect of single and fractional irradiation on normal and tumor tissues with similar mitotic activity

✍ Scribed by I. V. Shiffer


Publisher
Springer US
Year
1969
Tongue
English
Weight
262 KB
Volume
67
Category
Article
ISSN
0007-4888

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The amino acid analog azetidine-2-carboxylic acid (azetidine) is a potent sensitizer to both hyperthermia and ionizing radiation. Incubation of H35 hepatoma cells with 2.5 mM azetidine before or after treatments with X-rays causes a time-and sequencedependent enhancement of cell killing. Exposure of