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Effect of simvastatin, ursodeoxycholic acid and simvastatin plus ursodeoxycholic acid on biliary lipid secretion and cholic acid kinetics in nonfamilial hypercholesterolemia

โœ Scribed by Giuseppe Mazzella; Paolo Parini; Davide Festi; Franco Bazzoli; Rita Aldini; Aldo Roda; Domenica Tonelli; Antonio Cipolla; Antonio Salzetta; Prof. Enrico Roda


Publisher
John Wiley and Sons
Year
1992
Tongue
English
Weight
726 KB
Volume
15
Category
Article
ISSN
0270-9139

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In five patients with radiolucent gallstones, the effect of ursodeoxycholic acid (Urso) in doses of 250,500, 750, 1,000, and 1,250 mg per day on biliary lipid and bile acid composition was studied. Biliary cholesterol decreased from 8.8 f 0.8 mole% to 4.4 f 0.2 mole% at 500 mg Urso per day (7.1 mg p

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both bile acids, biliary cholesterol is transported in non-This study aimed to determine the effect in humans micellar aggregates. Finally, in the conditions of our of taurohyodeoxycholic acid, a 6a-hydroxylated bile acid study, taurohyodeoxycholic acid was not hepatotoxic. with hydrophilic properti

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Lipid Analysis. Serum cholesterol and triglyceride levels were decholesterol. [7][8][9][10][11][12] The latter should result in a compensatory termined using standard hospital laboratory methods. 23,24 Serum free and esterified methylated cholesterol precursor sterols lanosterol, D 8,24 -dimethylste