In five patients with radiolucent gallstones, the effect of ursodeoxycholic acid (Urso) in doses of 250,500, 750, 1,000, and 1,250 mg per day on biliary lipid and bile acid composition was studied. Biliary cholesterol decreased from 8.8 f 0.8 mole% to 4.4 f 0.2 mole% at 500 mg Urso per day (7.1 mg p
Effect of simvastatin, ursodeoxycholic acid and simvastatin plus ursodeoxycholic acid on biliary lipid secretion and cholic acid kinetics in nonfamilial hypercholesterolemia
โ Scribed by Giuseppe Mazzella; Paolo Parini; Davide Festi; Franco Bazzoli; Rita Aldini; Aldo Roda; Domenica Tonelli; Antonio Cipolla; Antonio Salzetta; Prof. Enrico Roda
- Publisher
- John Wiley and Sons
- Year
- 1992
- Tongue
- English
- Weight
- 726 KB
- Volume
- 15
- Category
- Article
- ISSN
- 0270-9139
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๐ SIMILAR VOLUMES
We have compared the effect of ursodeoxycholic acid with placebo on the clinical state, blood liver chemistries and serum and urinary bile acids in four patients with primary biliary cirrhosis. All parameters were evaluated monthly, and bile acid composition was measured by capillary gas-liquid chro
To test whether de nouo synthesis of cholesterol is a limiting factor for bile acid synthesis, we studied the acute effect of simvastatin, an inhibitor of HMGcoenzyme A reductase (the limiting step of cholesterol synthesis) on bile acid synthesis and biliary lipid secretion in subjects with interrup
both bile acids, biliary cholesterol is transported in non-This study aimed to determine the effect in humans micellar aggregates. Finally, in the conditions of our of taurohyodeoxycholic acid, a 6a-hydroxylated bile acid study, taurohyodeoxycholic acid was not hepatotoxic. with hydrophilic properti
Lipid Analysis. Serum cholesterol and triglyceride levels were decholesterol. [7][8][9][10][11][12] The latter should result in a compensatory termined using standard hospital laboratory methods. 23,24 Serum free and esterified methylated cholesterol precursor sterols lanosterol, D 8,24 -dimethylste