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Effect of simvastatin in familial hypercholesterolemia on the affinity of electronegative low-density lipoprotein subfractions to the low-density lipoprotein receptor

✍ Scribed by Sonia Benítez; Jordi Ordóñez-Llanos; Miquel Franco; Carmen Marín; Elier Paz; José López-Miranda; Carles Otal; Francisco Pérez-Jiménez; José Luis Sánchez-Quesada


Book ID
113440671
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
154 KB
Volume
93
Category
Article
ISSN
0002-9149

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✍ Tohru Funahashi; Yasuko Miyake; Akira Yamamoto; Yuji Matsuzawa; Bun-ichiro Kishi 📂 Article 📅 1988 🏛 Springer 🌐 English ⚖ 595 KB

Mutations of the low density lipoprotein (LDL) receptor in 16 Japanese kindreds with homozygous familial hypercholesterolemia (FH) were studied using an anti-LDL receptor antibody. The LDL receptor mutations in Japanese FH were heterogeneous and included defects in synthesis, post-translational proc