Effect of Silymarin Supplement on the Pharmacokinetics of Rosuvastatin
β Scribed by Jian Wei Deng; Ji-Hong Shon; Ho-Jung Shin; Soo-Jin Park; Chang-Woo Yeo; Hong-Hao Zhou; Im-Sook Song; Jae-Gook Shin
- Publisher
- Springer US
- Year
- 2008
- Tongue
- English
- Weight
- 239 KB
- Volume
- 25
- Category
- Article
- ISSN
- 0724-8741
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Silymarin, an extract from milk thistle (Silybum marianum), and its purified flavonolignans have been recently shown to inhibit hepatitis C virus (HCV) infection, both in vitro and in vivo. In the current study, we further characterized silymarin's antiviral actions. Silymarin had antiviral effects
## Abstract Recent studies reported that 3βhydroxyβ3βmethylβglutaryl coenzyme A (HMGβCoA) reductase inhibitors have pleotropic effects independent of their lipidβlowering properties. The present study was undertaken to determine whether treatment with rosuvastatin (RO) would be beneficial in a rat