𝔖 Bobbio Scriptorium
✦   LIBER   ✦

EFFECT OF SERUM WITHDRAWAL ON THE PROLIFERATION OF B16F10 MELANOMA CELLS

✍ Scribed by Clara Rodriguez-Ayerbe; Isabel Smith-Zubiaga

Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
92 KB
Volume
24
Category
Article
ISSN
1065-6995

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

B16F10 murine melanoma cell proliferation was inhibited after 48h in medium with serum in the range 0.1 to 0.5% by volume. Cell viability was mostly retained, whereas cells completely deprived of serum died. Growth‐arrested cultures showed serum‐dependent suppression of DNA synthesis. The response was typically that of a ‘cell cycle freeze’, verified by flow cytometric distribution of cells. Consequently, serum deprivation did not lead to synchony when serum was restored to arrested populations. Furthermore, there was no change in PCNA expression in arrested cells.

📜 SIMILAR VOLUMES

Interactions of B16F10 melanoma cells ag
Interactions of B16F10 melanoma cells aggregated on a cellulose substrate
✍ M. Hindié; M. Vayssade; M. Dufresne; S. Quéant; R. Warocquier-Clérout; G. Legeay 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 214 KB

## Abstract There is evidence that the shape of cells and their contact with a matrix direct the growth and the differentiation of both normal and cancer cells. Cells in 3D culture resemble the in vivo situation more closely than do those in conventional 2D cultures. We have studied the interaction

Inhibitory effect of the polyinosinic-po
Inhibitory effect of the polyinosinic-polycytidylic acid/cationic liposome on the progression of murine B16F10 melanoma
✍ Taku Fujimura; Satoshi Nakagawa; Tomoyuki Ohtani; Yumiko Ito; Setsuya Aiba 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 531 KB

## Abstract Cellular proteins, retinoic acid inducible gene‐I and Toll‐like receptor 3, sense dsRNA including polyinosinic‐polycytidylic acid (PIC) to stimulate innate immune response. The local administration of PIC has been demonstrated to be effective in anti‐tumor immunotherapy. However, the ef

The molecular mechanisms of vitamin C on
The molecular mechanisms of vitamin C on cell cycle regulation in B16F10 murine melanoma
✍ Eunsil Hahm; Dong-Hoon Jin; Jae Seung Kang; Young-In Kim; Seung-Woo Hong; Seung 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 227 KB

## Abstract Vitamin C has inconsistent effects on malignant tumor cells, which vary from growth stimulation to apoptosis induction. It is well known that melanoma cells are more susceptible to vitamin C than any other tumor cells, but the precise mechanism remains to be elucidated. In the present s

Suramin augments the antitumor and antim
Suramin augments the antitumor and antimetastatic activity of pentoxifylline in B16F10 melanoma
✍ Pooja Dua; Arvind Ingle; Rajiv P. Gude 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 French ⚖ 683 KB

## Abstract Rapid tumor growth and metastasis are 2 major problems associated with treatment of malignant melanoma. Therefore, drugs that can intervene these processes are of clinical importance. Pentoxifylline (PTX), a methyl xanthine derivative, has been shown to inhibit B16F10 melanoma tumor gro

Neoadjuvant immunotherapy with interfero
Neoadjuvant immunotherapy with interferon of the spontaneously metastasizing murine B16F10L melanoma
✍ Svetomir N. Markovic; Donna M. Murasko 📂 Article 📅 1990 🏛 John Wiley and Sons 🌐 French ⚖ 919 KB

We have previously demonstrated that administration of interferon a/b (IFN) for 4-5 days after challenge with a transplantable Moloney sarcoma virus-induced tumor completely inhibited tumor development. In the present study, we examined the therapeutic effects of IFN on mortality induced by metastat

Influence of cultivation, trypsinization
Influence of cultivation, trypsinization and aggregation on the transplantability of melanoma B16 cells
✍ Björn Hagmar; Klas Norrby 📂 Article 📅 1973 🏛 John Wiley and Sons 🌐 French ⚖ 961 KB

## Abstract To elucidate the usefulness of tumour cells grown __in vitro__ for transplantation studies, Melanoma B16 was grown in monolayer culture. Three types of suspensions were prepared from the cell cultures: two virtually monocellular suspensions, one produced by mechanical procedures and Ver