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Effect of sampling on topology predictions of protein-protein interaction networks

โœ Scribed by Han, Jing-Dong J; Dupuy, Denis; Bertin, Nicolas; Cusick, Michael E; Vidal, Marc


Book ID
109909022
Publisher
Nature Publishing Group
Year
2005
Tongue
English
Weight
536 KB
Volume
23
Category
Article
ISSN
1087-0156

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## Abstract A new method is described for prediction of protein membrane topology (intraโ€ and extracellular sidedness) from multiply aligned amino acid sequences after determination of the membraneโ€spanning segments. The prediction technique relies on residue compositional differences in the protei