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Effect of ryanodine on calcium release channel of the sarcoplasmic reticulum of skeletal muscle made open by phygiological stimuli

โœ Scribed by M. Endo; M. Tsukioka; H. Oyamada; M. Iino

Book ID
115885273
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
248 KB
Volume
183
Category
Article
ISSN
0014-2999

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Ryanodine as a functional probe of the s
Ryanodine as a functional probe of the skeletal muscle sarcoplasmic reticulum Ca2+release channel
โœ Gerhard Meissner; Anita El-Hashem ๐Ÿ“‚ Article ๐Ÿ“… 1992 ๐Ÿ› Springer ๐ŸŒ English โš– 336 KB

Ryanodine is a neutral plant alkaloid which functions as a probe for an intracellular Ca2+ release channel (ryanodine receptor) in excitable tissues. Using [3H]ryanodine, a 30 S protein complex comprised of four polypeptides of Mr 565,000 has been isolated and functionally reconstituted into planar