Effect of root canal sealers on mouse peritoneal macrophage functions
✍ Scribed by I. Brekalo; S. Pezelj-Ribarić; M. Abram; V. Ahel
- Publisher
- Springer Netherlands
- Year
- 2007
- Tongue
- English
- Weight
- 131 KB
- Volume
- 52
- Category
- Article
- ISSN
- 0015-5632
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## Abstract Excessive production of nitric oxide (NO) is associated with inflammation. In the present study, we examined the effects of root canal sealers (N2 Universal, Sealapex, and AH26) on NO production and inducible NO synthase (iNOS) expression in lipopolysaccharide (LPS)‐stimulated RAW 264.7
## Abstract Cyclooxygenase‐2 (COX‐2) is an inducible enzyme believed to be responsible for prostaglandin synthesis at site of inflammation. Recently, the activation of COX‐2 expression may be one of the important pathogenesis of root‐canal‐sealers–induced periapical inflammation. However, little is