Effect of rhDNase on lung function and quality of life in adult cystic fibrosis patients
โ Scribed by H.G.M. Heijerman; R.N. van Rossem; W. Bakker
- Book ID
- 116120957
- Publisher
- Elsevier Science
- Year
- 1995
- Tongue
- English
- Weight
- 406 KB
- Volume
- 46
- Category
- Article
- ISSN
- 0300-2977
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The majority of patients with cystic fibrosis (CF) will grow into adulthood. Despite this improvement in survival, the disease is progressive, especially with respect to the decline in pulmonary function, which in turn may have an impact on a patient's quality of life. In this study we evaluated the
The aim of the study was to measure the effect of a short course of recombinant human deoxyribonuclease I (rhDNase) on ciliary and cough clearance in a group of cystic fibrosis patients, using a radioaerosol and gamma camera technique. Patients were initially randomized to receive either rhDNase (2.