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Effect of renal failure on the pharmacokinetics of acyclovir

โœ Scribed by Oscar L. Laskin; James A. Longstreth; Andrew Whelton; Harvey C. Krasny; Ronald E. Keeney; Laura Rocco; Paul S. Lietman

Book ID
115678883
Publisher
Elsevier Science
Year
1982
Tongue
English
Weight
545 KB
Volume
73
Category
Article
ISSN
1555-7162

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Pharmacokinetic parameters of oltipraz were compared after intravenous and oral administration at a dose of 30 mg/kg to control rats and rats with U-ARF. After intravenous administration to rats with U-ARF, the AUC was significantly greater (1100 versus 1730 mg ร min/mL) than that in control rats, a