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Effect of reducing the top concentration used in the in vitro chromosomal aberration test in CHL cells on the evaluation of industrial chemical genotoxicity

โœ Scribed by Takeshi Morita; Masamitsu Honma; Kaoru Morikawa


Book ID
116759998
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
808 KB
Volume
741
Category
Article
ISSN
1383-5718

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Different test results have been reported for the same were obtained in both cell types, CHL cells sometimes chemicals in two in vitro chromosome aberration had higher aberration levels and survived at higher test systems, CHL cells tested by a Japanese protocol doses than CHO cells would tolerate.