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Effect of receptor binding domain mutations on receptor binding and transmissibility of avian influenza H5N1 viruses

✍ Scribed by Taronna R. Maines; Li-Mei Chen; Neal Van Hoeven; Terrence M. Tumpey; Ola Blixt; Jessica A. Belser; Kortney M. Gustin; Melissa B. Pearce; Claudia Pappas; James Stevens; Nancy J. Cox; James C. Paulson; Rahul Raman; Ram Sasisekharan; Jacqueline M. Katz; Ruben O. Donis

Book ID: 113948277
Publisher: Elsevier Science
Year: 2011
Tongue: English
Weight: 963 KB
Volume: 413
Category: Article
ISSN: 0042-6822
DOI: 10.1016/j.virol.2011.02.015

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## Abstract In order to identify molecular changes associated with the transmission of avian influenza A H5N1 and H9N2 viruses to humans, the internal genes from these viruses were compared to sequences from other avian and human influenza A isolates. Phylogenetically, each of the internal genes of