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Effect of pyrroxan and butyroxan on noradrenalin storage and release in the albino rat brain

โœ Scribed by M. P. Podosinovikova; A. V. Lychakov; S. S. Krylov; N. T. Starykh

Publisher
Springer US
Year
1982
Tongue
English
Weight
239 KB
Volume
93
Category
Article
ISSN
0007-4888

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Effects of pyrroxan and chlordiazepoxide
Effects of pyrroxan and chlordiazepoxide on biogenic amine metabolism in the rat brain
โœ T. A. Pugsley; W. Lippmann ๐Ÿ“‚ Article ๐Ÿ“… 1976 ๐Ÿ› Springer ๐ŸŒ English โš– 631 KB

Pyrroxan (20 mg/kg, i.p.) , a new potential antianxiety agent, increased brain norepinephrine (NE) turnover in rats, reflecting a possible central e-adrenergic receptor blocking activity, in contrast, chlordiazepoxide (20 mg/kg, i.p.), a widely used antianxiety agent, did not alter the NE turnover.