## Abstract The production of early and term placental alkaline phosphatase (ALP), human chorionic gonadotropin betasubunit (β‐hCG) and pregnancy‐specific beta~1~‐glycoprotein (SP~1~) was confirmed in the newly established uterine cervical cancer call line SKG‐IIIa. Treatment of these cells in cult
✦ LIBER ✦
Effect of pyrimidine deoxynucleosides and sodium butyrate on expression of the glycoprotein hormone α-subunit and placental alkaline phosphatase in HeLa cells
✍ Scribed by Richard N. Tamura; G.Stanley Cox
- Book ID
- 119120661
- Publisher
- Elsevier Science
- Year
- 1988
- Tongue
- English
- Weight
- 665 KB
- Volume
- 968
- Category
- Article
- ISSN
- 0167-4889
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Expression of the MDR I (P-glycoprotein) gene confers resistance to several classes of chemotherapeutic drugs (multi-drug resistance). Colon carcinomas frequently express high levels of MDR I mRNA and P-glycoprotein, presumably reflecting the origin of these tumors from MDRl -expressing normal colon