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Effect of putative carcinoid mediators on gastric and small bowel transit in rats and the role of 5-HT receptors

โœ Scribed by M. A. VALDOVINOS; G. M. THOMFORDE; M. CAMILLERI


Book ID
108603148
Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
522 KB
Volume
7
Category
Article
ISSN
0269-2813

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The effects of a 5-HT1receptor ligand is
โœ G. M. Goodwin; Rosemarie J. Souza; A. R. Green ๐Ÿ“‚ Article ๐Ÿ“… 1986 ๐Ÿ› Springer ๐ŸŒ English โš– 557 KB

The effects of 2-(4-(4-(2-pyrimidinyl)-l-piperazinyl)-butyl)-1,2-benzoisothiazol-3(2H)one-1,1-dioxide hydrochloride (isapirone, TVX Q 7821), a putative 5-HT1 receptor antagonist, has been studied on various models of 5-HT receptor sub-type function. In mice TVX Q 7821 produced a dose-dependent inhib