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Effect of PSI-697, a Novel P-Selectin Inhibitor, on Platelet-Monocyte Aggregate Formation in Humans

โœ Scribed by Japp, A. G.; Chelliah, R.; Tattersall, L.; Lang, N. N.; Meng, X.; Weisel, K.; Katz, A.; Burt, D.; Fox, K. A. A.; Feuerstein, G. Z.; Connolly, T. M.; Newby, D. E.


Book ID
126317758
Publisher
Ovid Technologies Wolters Kluwer -American Heart Association
Year
2013
Tongue
English
Weight
767 KB
Volume
2
Category
Article
ISSN
2047-9980

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โœ Tsunehiko Kuzuya; Yoshihiro Kimura; Shiro Hoshida; Kazuhisa Kodama; Nobuto Nakam ๐Ÿ“‚ Article ๐Ÿ“… 1988 ๐Ÿ› Springer US ๐ŸŒ English โš– 585 KB

The pharmacokinetics and pharmacologic effects of a potent, selective inhibitor of thromboxane synthetase, CV-4151 [(E)-7-phenyl-7-(3-pyridyl)-6-heptenoic acid] on prostanoid formation and platelet aggregation were studied in 42 healthy male volunteers. The drug was well tolerated. After oral admini