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Effect of proteoglycans on type I collagen fibre formation

✍ Scribed by Atul K Garg; Richard A Berg; Frederick H Silver; Hari G Garg

Publisher
Elsevier Science
Year
1989
Tongue
English
Weight
916 KB
Volume
10
Category
Article
ISSN
0142-9612

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## Abstract Non‐enzymatic glycation of type I collagen occurs in aging and diabetes, and may affect collagen solubility, charge, polymerization, and intermolecular interactions. Proteoglycans^1^ (PGs) bind type I collagen and are proposed to regulate fibril assembly, function, and cell–collagen int