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Effect of protein kinase C on amylase secretion and cyclic AMP production in rat pancreatic acinar cells

✍ Scribed by Ishizuka, Tatsuo ;Ito, Yasufumi ;Miura, Kiyoshi ;Nagao, Sciji ;Nozawa, Yoshinori

Publisher
Springer-Verlag
Year
1991
Tongue
English
Weight
803 KB
Volume
26
Category
Article
ISSN
0435-1339

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The effects of phorbol myristate acetate (PMA) and dexamethasone on protein kinase C (PK-C) activity and eicosanoid production were characterized in primary cultures of rat glial cells. PMA (1,000 ng/ml) treatment for 2 hr resulted in a maximal effect (a 4-fold increase in PGE, production). Longer e