Effect of protein binding on the pharmacodynamics of an HIV protease inhibitor: C. Flexner, D.D. Richman, M. Bryant, A. Karim, P. Yeramian, P. Meehan, R. Haubrich, M.F. Para, M.A. Fischl, and the AIDS Clinical Trials Group (ACTG) 282 Study Team. The Johns Hopkins University School of Medicine, Baltimore, Maryland, the University of California, San Diego, Searle R & D, Skokie, Illinois, Ohio State University, and the University of Miami, USA