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Effect of promoter strength on protein expression and immunogenicity of an HSV-1 amplicon vector encoding HIV-1 Gag

✍ Scribed by Kathlyn Santos; Cindy M.P. Duke; Sol M. Rodriguez-Colon; Anthony Dakwar; Shongshan Fan; Michael C. Keefer; Howard J. Federoff; John G. Frelinger; William J. Bowers; Stephen Dewhurst


Book ID
116959412
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
531 KB
Volume
25
Category
Article
ISSN
0264-410X

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## Abstract It has been demonstrated previously that a human immunodeficiency virus (HIV) type 1 Gag mutant (MA2) with a tandem repeat of 107‐matrix codons in the matrix domain could direct virus particle assembly and budding [Wang et al. (2000c): J Med Virol 61:423–432]. Since the regions involved