Effects of prochlorperazine on experimen
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Steadman D. Harrison; Jana L. Cox; Ralph C. Giles
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Article
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1982
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Springer
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English
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In early studies of the antitumor drug 1-(2-chloroethyl)-3-(4-methylcyclohexyl)-1nitrosourea (methyl-CCNU), animal models consistently predicted that the compound would be nephrotoxic in humans. Nephrotoxicity in cancer patients who had received methyl-CCNU was not confirmed until about 6 years afte