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Effect of procarbazine and cyclophosphamide on chromosome breakage in Fanconi anemia cells: Relevance to bone marrow transplantation

✍ Scribed by Arleen D. Auerbach; Barbara Adler; Richard J. O'Reilly; Dahlia Kirkpatrick; R.S.K. Chaganti


Book ID
119102681
Publisher
Elsevier Science
Year
1983
Tongue
English
Weight
825 KB
Volume
9
Category
Article
ISSN
0165-4608

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The in vivo SCE formation and the induction of chromosome aberrations in the bone marrow of Chinese hamsters (Cricetulus griseus) were studied after various concentrations of cyclophosphamide, and the sensitivity of the two test methods was compared. The administraiton of 1.0, 5.0, 13.3, 25.0, and 4