Effect of polyphenolic extracts from red wine and 4–OH–coumaric acid on 1,2–dimethylhydrazine–induced colon carcinogenesis in rats

Enhancing effects of simultaneous treatm

Enhancing effects of simultaneous treatment with sodium nitrite on 2-amino-3-methylimidazo[4,5-f]quinoline-induced rat liver, colon and Zymbal's gland carcinogenesis after initiation with diethylnitrosamine and 1,2-dimethylhydrazine

✍ Yasuki Kitamura; Takashi Umemura; Kazushi Okazaki; Keita Kanki; Takayoshi Imazaw 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 French ⚖ 150 KB

## Abstract Combined effects of sodium nitrite (NaNO~2~) and 2‐amino‐3‐methylimidazo[4,5‐__f__]quinoline (IQ) on liver, colon and Zymbal's gland carcinogenesis were assessed using a rat two‐stage carcinogenesis model, with a focus on involvement of oxidative stress. Male 6‐week‐old F344 rats were g