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Effect of polymorphism in insulin locus and HLA on type 1 diabetes in four ethnic groups in Israel

✍ Scribed by G. Benedek; C. Brautbar; P. Vardi; N. Sharon; N. Weintrob; A. Zung; S. Israel


Book ID
110892880
Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
104 KB
Volume
73
Category
Article
ISSN
0001-2815

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We analyzed 88 unrelated subjects with Type 1 (insulin-dependent) diabetes and 64 sibling controls (maximum one per diabetic) for associations between immunoglobulin allotype antigens (GM and KM) and Type 1 diabetes. None were found. However, we did find interactions between GM, HLA-DR, and Type 1 d