Effect of polyanionic compounds on intracutaneous and intravaginal herpes virus infection in mice: Impact on the search for vaginal microbicides

Hydrogels containing monocaprin prevent

Hydrogels containing monocaprin prevent intravaginal and intracutaneous infections with HSV-2 in mice: Impact on the search for vaginal microbicides

✍ Neyts, Johan; Kristmundsd�ttir, T.; De Clercq, Erik; Thormar, Halldor 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 156 KB

Hydrogel formulations containing the 1-monoglyceride of capric acid (monocaprin) possess potent in vitro microbicidal activity against HIV and HSV, Chlamydia trachomatis and Neisseria gonorrhoeae. These formulations were studied to determine whether they prevent intracutaneous and intravaginal infec