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Effect of poly(ADP-ribosyl)ation inhibitors on the genotoxic effects of the boron neutron capture reaction

✍ Scribed by Nuno G. Oliveira; Matilde Castro; António S. Rodrigues; Isabel C. Gonçalves; Célia Martins; José M. Toscano Rico; José Rueff

Book ID
116758960
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
208 KB
Volume
583
Category
Article
ISSN
1383-5718

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## Abstract Poly ADP‐ribosylation is a post‐translational modification of chromatin proteins catalyzed by the enzyme poly‐ADPR transferase (poly‐ADPRT) and affects the structure as well as the functional properties of chromatin. It is of particular relevance in carcinogenesis, as it represents an e