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Effect of Plasma-calcium-level-responsive Oestradiol Release from Apatitic Bone Cement on Bone Mineral Density in Ovariectomized Rats

✍ Scribed by MAKOTO OTSUKA; KAZUKI YONEOKA; YOSHIHISA MATSUDA; JEFFREY L. FOX; WILLIAM I. HIGUCHI

Book ID: 111769775
Publisher: Pharmaceutical Press
Year: 1999
Tongue: English
Weight: 248 KB
Volume: 51
Category: Article
ISSN: 2042-7158
DOI: 10.1211/0022357991772538

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## Abstract The purpose of this study was to evaluate the efficacy of zinc (Zn)‐containing β‐tricalcium phosphate (Zn–TCP) in correcting the bone mineral deficiency noted in osteoporosis using ovariectomized rat model. Four rats were used for each of the four experimental groups: D0, D10, D20, and