Effect of physical activity on lipid levels in a population-based sample of men with and without the Arg192 variant of the human paraoxonase gene
✍ Scribed by Mariano Sentí; Clara Aubó; Roberto Elosua; Joan Sala; Marta Tomás; Jaume Marrugat
- Publisher
- John Wiley and Sons
- Year
- 2000
- Tongue
- English
- Weight
- 36 KB
- Volume
- 18
- Category
- Article
- ISSN
- 0741-0395
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✦ Synopsis
the most favorable lipid profile in this genetic group. A statistically-significant interaction between paraoxonase genotypes and physical activity was observed for log triglycerides (P = 0.018), HDL-cholesterol concentration (P = 0.017), and log triglyceride-to-HDL-cholesterol ratio (P = 0.008). The beneficial association of the amount of physical activity and lipid traits found in men with the R allele suggests that this population subgroup needs to be physically active to achieve a favorable lipoprotein phenotype similar to that observed in QQ homozygous men.