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Effect of phenytoin on calcium disposition in pregnant and nonpregnant mice

โœ Scribed by Michael A. Evans


Book ID
113205905
Publisher
Elsevier Science
Year
1982
Tongue
English
Weight
583 KB
Volume
63
Category
Article
ISSN
0041-008X

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Effects of ibuprofen on the disposition
โœ Patricia A. Cleveland; Clarence T. Ueda ๐Ÿ“‚ Article ๐Ÿ“… 1985 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 529 KB

The effects of ibuprofen on maternal phenytoin pharmacokinetics and fetal phenytoin acquisition were investigated in 19-day gestation Sprague-Dawley rats. A 5 mg kg-' bolus injection of I4C-phenytoin was given with and without (control) pretreatment with 12.5 mg kg-' of ibuprofen. Maternal plasma an