Effect of phenylalanine-lysine-vasopressin on portal circulation
✍ Scribed by Hayasaka, S. ;Anju, T. ;Atsuta, T. ;Tsukada, M. ;Shiraishi, T. ;Matsushita, M. ;Yamazaki, H. ;Isomatsu, T. ;Sameshima, N. ;Sugie, S.
- Publisher
- Springer-Verlag
- Year
- 1968
- Tongue
- English
- Weight
- 72 KB
- Volume
- 3
- Category
- Article
- ISSN
- 0435-1339
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## Abstract A synthesis is described of the protected linear decapeptide: __N__‐benzyloxycarbonyl‐__S__‐benzyl‐__L__‐cysteinyl‐__L__‐tyrosyl‐__L__‐tyrosyl‐__L__‐tyrosyl‐__L__‐glutaminyl‐__L__‐asparaginyl‐__S__‐benzyl‐__L__‐cysteinyl‐__L__‐prolyl‐__N__^e^‐p‐toluene‐sulphonyl‐__L__‐lysylglycineamide
This study investigated the effect of vasopressin on portal-systemic collaterals in portal hypertensive rats and the influence of nitric oxide (NO) and prostaglandin on the responsiveness of collateral vessels to vasopressin. The vascular responsiveness to graded concentrations of vasopressin was te