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Effect of phenyl substitution on the structure and activity of 3-hydroxyimino-2-butanone thiosemicarbazone: structure of 3-hydroxyimino-2-butanone 4-phenylthiosemicarbazone

✍ Scribed by Nandi, A. K. ;Sheldrick, W. S. ;Ghosh, S. P.


Book ID
114503429
Publisher
International Union of Crystallography
Year
1986
Tongue
English
Weight
470 KB
Volume
42
Category
Article
ISSN
0108-2701

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## ABSTRACT Enantioselective syntheses of two stereoisomers of 3‐hydroxy‐4‐phenyl‐2‐butanone were investigated via Shi's asymmetric epoxidation or Sharpless asymmetric dihydroxylation of silyl enol ether. (__R__)‐3‐Hydroxy‐4‐phenyl‐2‐butanone was obtained in 73% enantiomeric excess (__ee__) by Shi'